Management of malignant melanoma of the head and neck.
نویسندگان
چکیده
A total of 91 patients with melanoma of the head and neck treated between 1973 and 1991 were studied prospectively with regard to prognostic features, treatment and outcome. Other than Breslow thickness, the only important prognostic feature was the less aggressive nature of lentigo maligna melanoma. A policy of selective excision margins, 1 cm for impalpable and 2 cm for palpable lesions, was found to be safe, although preliminary biopsy should be used if there is diagnostic uncertainty or where the expected extent of surgery entails a mutilating procedure. Local recurrence rates were not affected by the method of wound closure, which should be determined by the best functional and cosmetic outcome. These results support the trend against prophylactic neck dissection. Such dissection, when indicated for lesions of the face, pinna, anterior scalp and parotid area, should routinely include superficial parotidectomy. Uncontrolled symptomatic loco-regional recurrence is an uncommon complication that may occur despite radical primary surgery. The role of preoperative radiotherapy for high-risk melanoma in this situation warrants investigation.
منابع مشابه
Malignant Melanoma of the External Auditory Canal:A Rare Entity
Introduction: Although malignant melanomas (MM) are common in the head and neck region; primary malignant melanoma of the external auditory canal (EAC) is rare. Case Report: We present the case of a 50-year-old symptomatic man with a malignant melanoma of the external auditory canal, which clinically masqueraded as a haemangioma. The patient subsequently developed extensive loco-regional me...
متن کاملویژگیهای دموگرافیک و بالینی مبتلایان به ملانوم بدخیم مراجعهکننده به یک درمانگاه مرجع تومورهای پوست در ایران: مطالعهای 5 ساله
Background and Aim: Malignant melanoma is one of the most lethal skin tumors. Its prevalence and demographic specifications are different in European and western countries from those in the Middle East. This study was aimed to evaluate the demographic and clinical characteristics of malignant melanoma in Iran. Methods: In this cross-sectional study, the patients with the diagnosis of malignant...
متن کاملتحلیل بقا در مبتلایان به ملانوم بدخیم در یزد
Background and Aim: Malignant melanoma is a rare and most malignant type of skin cancer which is originated from melanocytes. It is capable of infiltrating into interior organs and could cause mortality. The aim of this study is to analyze the survival of patients with malignant melanoma according to their age, gender, mitosis count, tumor thickness, level of lymphocyte infiltration, tumor loca...
متن کاملDiagnosis and Management of a Malignant Dermal Melanoma in a Donkey (Equus asinus)
Case Description- A 2-yr-old intact male donkey (Equus asinus) was presented to Hospital of Veterinary Medicine, Mansoura University with subcutaneous masses under the tail. Clinical Findings- Physical examination revealed the presence of 2 separate 5x10 and 5x8-cm-diameter, round and firm subcutaneous masses. Treatment and Outcome<...
متن کاملFrequency of malignant skin tumors in renal transplant recipients in Imam Reza hospital of Mashhad, Iran
Background: The higher frequency of malignant skin tumors is of great significance in renal transplant recipients (RTRs) who should receive immunosuppressive therapy for a long time. This study was designed to determine the frequency of malignant skin tumors in RTRs in Imam Reza Hospital, Mashhad, Iran, in 2001-2002.Method: This descriptive study was performed on 322 recipients who were examine...
متن کاملMalignant Melanoma in a Female Mallard Duck (Anas platyrhynchos)
Melanomas are malignant neoplasms originating from melanocytes. They reported in birds. In this case, macroscopic and microscopic (the histopathologic and IHC) findings supported a final diagnosis of cutaneous malignant melanoma in a mallard duck (Anas platyrhynchos). A female mallard duck (Anas platyrhynchos) was observed with a mass on the ventral portion of the neck. Th...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Mayo Clinic proceedings
دوره 64 7 شماره
صفحات -
تاریخ انتشار 1989